Friday, 13 June 2014

Increasing incidence of invasive aspergillosis in France

A new population-based analysis by Bitar et al. at the Institute of Health Surveillance, Paris, reveals an increasing incidence of invasive fungal infections (IFIs) in France. Using a national hospital database, inclusive of more than 95% of French hospitals, hospital stays from 2001-2010 were reviewed for invasive fungal infections.

From 35,876 IFI cases, invasive aspergillosis (IA) accounted for over a quarter, and alongside Candida spp. infections made up the majority of mortality—together accounting for over 87% of deaths. However the study also showed that IA fatality is reducing by 1.4% per year, despite overall incidence of IFIs–including IA–in the general population increasing by 1.5%.

The study reveals worrying trends that increasing numbers of immunocompromised patients are being affected by IFIs. Whilst the overall trend of reducing mortality in IA is a positive, future work needs to find a way of managing at-risk populations to reduce the number of cases.

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