From 35,876 IFI cases, invasive aspergillosis (IA) accounted for over a quarter, and alongside Candida spp. infections made up the majority of mortality—together accounting for over 87% of deaths. However the study also showed that IA fatality is reducing by 1.4% per year, despite overall incidence of IFIs–including IA–in the general population increasing by 1.5%.
The study reveals worrying trends that increasing numbers of immunocompromised patients are being affected by IFIs. Whilst the overall trend of reducing mortality in IA is a positive, future work needs to find a way of managing at-risk populations to reduce the number of cases.