Monday, 5 May 2014

Opportunistic Infection Incidence Rises During Treatment for HIV in Japanese Study


Opportunistic infections and malignancies such as malignant lymphoma and Kaposi sarcoma are significant complications of human immunodeficiency virus (HIV) infection. However, following the introduction of antiretroviral therapy in Japan in 1997, the incidence of clinical complications has decreased. In the present study, autopsy cases of HIV infection in Japan were retrospectively investigated to reveal the prevalence of opportunistic infections and malignancies.

A total of 225 autopsy cases of HIV infection identified at 4 Japanese hospitals from 1985– 2012 were retrospectively reviewed. Clinical data were collected from patient medical
records.

Results showed that although the incidence of viral infection other than HIV fell after treatment for HIV, teheh incidence of other opportunistic infections - including aspergillosis - rose. The authors conclude that monitoring for such opportunistic infection should be maintained in AIDS patients regardless of whether or not they are being treated with antiviral medication.

Full article can be read here


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