Serum was tested from 101 patients after undergoing an allogeneic stem cell transplantation.By the end of hospitalisation, one proven, nine probable and 20 possible cases of invasive fungal infection were identiﬁed.
The Aspergillus-LFD showed a comparable diagnostic performance to the GM-EIA. However, if the results have to be conﬁrmed by a second positive serum, then the GM-EIA exhibited a superior sensitivity.
Comparing the 2 methods in terms of practicability, the Aspergillus-LFD was demonstrated to be a quick (15 min) and easy-to-use test for single-patient detection of Aspergillus antigens or to rule them out, but not if more than one positive serum is required. Link